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应用放射免疫法测定了30例慢性肾衰和10例正常人的血清甲状旁腺激素(PTH);结果慢性肾衰的PTH 值明显高于正常值,分别为4.53±0.48和0.48±0.05ngEg/ml,且随着肌酐清除率(Cer)的下降而逐渐升高。对PTH 增高的临床意义进行了讨论,认为PTH 可作为慢性肾衰患者继发性甲旁亢的早期诊断指标。
Serum parathyroid hormone (PTH) was measured by radioimmunoassay in 30 cases of chronic renal failure and 10 cases of normal people. Results The PTH of chronic renal failure was significantly higher than the normal values of 4.53 ± 0.48 and 0.48 ± 0.05 ngEg / ml, and gradually increased with the decline of creatinine clearance (Cer). The clinical significance of elevated PTH was discussed, that PTH can be used as an early diagnosis of secondary hyperparathyroidism in patients with chronic renal failure.