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新生儿颅内出血(intracranial hemorrhage,ICH)是围生期新生儿常见的脑损伤,不仅有较高的病死率,而且存活者中部分留有永久性神经系统后遗症。早期发现、合理治疗、积极预防是围生医学的重要课题。现将ICH在病因、诊断、治疗、预防方面的国内外研究进展综述如下。1病因1.1母亲孕产期情况:Zakhary[1]回顾性调查了798例ICH患儿,显示母亲孕产期患病将影响胎儿脑部正常发育,前3位疾病依次为子痫前期-子痫、胎盘早剥和子宫异常。
Neonatal intracranial hemorrhage (ICH) is a common brain injury in perinatal neonates, not only having a high mortality but also having permanent neurological sequelae in some of the survivors. Early detection, rational treatment, active prevention is an important issue in perinatal medicine. Now ICH etiology, diagnosis, treatment, prevention of domestic and foreign research progress are summarized below. 1 Etiology 1.1 Maternal status of mother: Zakhary [1] A retrospective survey of 798 children with ICH, shows that the mother’s maternal period will affect the normal fetal brain development, the top three diseases were preeclampsia - eclampsia , Placental abruption and abnormal uterus.