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作者报告和分析了16例经病毒培养和组织学证实的细胞巨病毒(CMV)肺部感染,均为接受器官移植或有原发性肿瘤性疾病,并应用皮质类固醇抑制和化疗者,临床症状通常有发热、干咳、呼吸困难并有明显的低氧血症,其中6例入院时氧分压低于6θ,另外6例住院期间发生这种情况,这12例中11例均因低氧血症致死,而另3例无低氧血症者均存活。胸部X线检查16例中13例的主要表现为弥漫性间质性或肺泡性浸润,其余3例尚有其他表现(结节、空洞)。呼吸系统症状持续1～7周不等,住院期间疾病转归不一致,有些存活者肺部表现逐渐好转,X线征象在几周内消散,有存活者呼吸衰竭迅速进展而另一些患者由于呼吸衰竭进展迅速而致死亡。在生前经肺活检或抽吸作
The authors reported and analyzed 16 cases of cytomegalovirus (CMV) pulmonary infection confirmed by virus culture and histology. All of them were undergoing organ transplantation or had primary tumor diseases. Patients with corticosteroid suppression and chemotherapy, clinical symptoms Usually have fever, dry cough, difficulty breathing and obvious hypoxemia, of which 6 patients admitted to the oxygen partial pressure lower than 6 theta, while the other 6 cases occurred during hospitalization, of which 12 cases were due to hypoxemia Mortality, while the other three patients without hypoxemia were alive. Chest X-ray examination in 16 cases, 13 cases of the main manifestations of diffuse interstitial or alveolar infiltration, and the remaining three cases there are other manifestations (nodules, empty). Respiratory symptoms ranged from 1 to 7 weeks, with varying degrees of hospitalization during hospitalization, with some survivors progressing progressively in the lungs, X-ray signs dissipating within weeks, survivors with rapid respiratory failure, and others with respiratory failure Rapid progress and death. Through the lung biopsy or suction during her lifetime