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基于溃疡性结肠炎病因学可能与免疫机制有关,直肠粘膜嗜酸性细胞计数(EC)被认为可预测疾病的严重度和预后;然而,对此尚存有争议。本研究在治疗前后作EC和肥大细胞计数,以观察二者与本病的关系。方法:选择44例(男18,女26)平均年龄32.2士14,7岁的活动性溃疡性结肠炎病人进行研究。溃结诊断的依据为①慢性腹泻伴血便和粘液便,抗菌及抗阿米巴治疗无效;②2次新鲜粪检查寄生虫阴性而乙结肠镜发现粘膜充血水肿、溃疡形成,颗粒状及脆性增加。按病情分为轻、中、重度,活动和非活动型,乙结肠镜分类则根据Binder标准,每例均取直肠活检。所有病人均
Based on the etiology of ulcerative colitis that may be related to immune mechanisms, rectal mucosal eosinophil counts (ECs) are thought to predict the severity and prognosis of the disease; however, there is debate. The study before and after treatment for EC and mast cell count to observe the relationship between the two and the disease. Methods: A total of 44 patients (18 males and 26 females) with active ulcerative colitis (32.2 ± 14.7 years) were selected for study. The basis of ulceration diagnosis is ① chronic diarrhea with bloody stools and mucus will be antibacterial and anti-amoebic treatment is invalid; ② 2 fresh fecal negative examination of parasite and colonoscopy found mucosal congestion and edema, ulcer formation, increased granular and brittleness. According to the disease is divided into mild, moderate, severe, active and inactive type, according to Binder colonoscopy classification, each case were taken rectal biopsy. All patients are