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目的探讨胺碘酮治疗心力衰竭合并心律失常患者的临床效果。方法选取2013年10月至2016年1月辽宁鞍山市海城市中心医院收治的93例心力衰竭合并心律失常患者作为研究对象,根据抽签法将其分为对照组(46例)和观察组(47例)。对照组患者行常规抗心力衰竭治疗,观察组患者在对照组基础上加服胺碘酮,比较两组患者的临床疗效、心电图变化、抗室速有效率、猝死率、不良反应发生情况。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的抗室速有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的左心室EP明显高于对照组,静息心率明显低于对照组,Q-T间期明显长于对照组,差异均有统计学意义(均P<0.05)。结论在心力衰竭合并心律失常患者的临床治疗中应用胺碘酮,可显著提高临床疗效,改善患者心脏功能,且安全性较高。
Objective To investigate the clinical effect of amiodarone in patients with heart failure and arrhythmia. Methods A total of 93 patients with heart failure and arrhythmia admitted from Haicheng Central Hospital of Anshan City in Liaoning Province from October 2013 to January 2016 were selected as study subjects and divided into control group (46 cases) and observation group (47 cases) according to the drawing method example). Patients in the control group were treated with conventional anti-heart failure. Patients in the observation group were treated with amiodarone on the basis of the control group. Clinical efficacy, electrocardiogram changes, effective rate of anti-ventricular tachycardia, sudden death and adverse reactions were compared between the two groups. Results The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05); the effective rate of anti-ventricular tachycardia in observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05 ). The left ventricle EP in the observation group was significantly higher than that in the control group, resting heart rate was significantly lower than that in the control group, QT interval was significantly longer than the control group, the difference was statistically significant (P <0.05). Conclusions The application of amiodarone in the clinical treatment of patients with heart failure and arrhythmia can significantly improve the clinical efficacy, improve the cardiac function and have higher safety.