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206例各种不同部位恶性肿瘤，其血清铜和铜／锌比值均高于对照组；91例血清硒值均低于对照组。癌肿手术后未复发的病人，血清钢、硒值均恢复至正常范围。76例肺癌按TNM分期，血清铜值Ⅳ＞Ⅲ＞Ⅱ＞Ⅰ期。胃肠癌组织中铜、硒含量均高于同源非癌胃、肠组织，（P＜0．01、0．05）。以上结果提示：恶性肿瘤病人铜、硒存在再分布现象，血清钢的升高及硒的降低可作为恶性肿瘤非特异性诊断，特别是疗效和预后判断指标。
The serum copper and copper/zinc ratios were higher in 206 patients with various sites than those in the control group; the serum selenium values in 91 patients were lower than those in the control group. In patients who did not relapse after surgery, serum steel and selenium values returned to normal ranges. 76 cases of lung cancer were classified by TNM, serum copper IV>III>II>I phase. The contents of copper and selenium in gastrointestinal cancer tissues were higher than those in homologous non-cancerous gastric and intestinal tissues (P<0.01, 0.05). The above results suggest that there are redistribution of copper and selenium in patients with malignant tumors. The increase of serum steel and the decrease of selenium can be used as non-specific diagnosis of malignant tumors, especially the indicators of efficacy and prognosis.