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为了从围产期角度观察出生前后游离氨基酸的发育动态变化并为临床提供必要生理参考值,本文根据围产期不同阶段分别测定了出生前妊娠中期及晚期的羊水(9例及11例)、出生时脐血(代表胎儿)及孕母血清(26例及30例)、出生后3个不同年龄组儿童血清(分别为24、30及35例)中的游离氨基酸值。结果表明:(1)中期妊娠羊水中大多数氨基酸高于晚期妊娠羊水,但羊水值又普遍低于脐血及孕母血清值;(2)脐血游离氨基酸值低于相应孕母值;(3)新生组大多数氨基酸值明显高于婴幼儿组,但是学龄期时又趋回升并接近新生儿组值,作者对上述观察结果作了讨论,并强调了提供这些游离氨基酸生理值对临床实践的必要性。
In order to observe the developmental changes of free amino acids before and after birth and provide necessary physiological reference value for perinatal period, amniotic fluid (9 cases and 11 cases) were measured in different stages of perinatal period. Serum (24, 30, and 35, respectively) in the cord blood (representing the fetus) at birth and in the maternal serum (26 and 30) and in 3 different age groups after birth. The results showed that: (1) The majority of amino acids in amniotic fluid in metaphase pregnancy were higher than that in late pregnancy, but the amniotic fluid value was generally lower than that in umbilical cord blood and maternal serum; (2) The values of free amino acids in umbilical cord blood were lower than the corresponding maternal values; 3) Most of the amino acids in the newborn group were significantly higher than those in infants and young children, but the trend toward recovery and close to the newborn group during school age was discussed by the authors and highlighted the clinical value of providing these free amino acids to clinical practice Necessity.