关于麻醉药过敏和过敏试验

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有些人往往把麻醉药所引起的意外死亡或反应,及皮肤试验出现的红肿,简单地看成是“药物过敏”。若认真调查研究,就会发现常常不是这么一回事。事实上药物过敏是较为少见的,例如Moore(1955)指出:“麻醉药所致的全身性反应,属于过敏者仅占2%,而98%全是中毒反应。”既然大多数不能列入过敏,那么,将它们同难以预料的过敏分开,就非常必要,否则对非过敏的反应,便容易不去追根究底,得出应有的经验教训。皮肤试验的红肿,可能是敏感反应,也可能是一种假象,与抗原和抗体的结合根本无关,但在外观上无法分辨。本文拟结合文献,对这些问题作一简要说明。首先介绍作者过去遇到的几个药量不大, Some people often think of the accidental death or reaction caused by narcotic drugs and the swelling in skin tests as “drug allergy”. If you carefully investigate the research, you will find that often not the same thing. In fact, drug allergies are rare. For example, Moore (1955) pointed out: “The general reaction caused by narcotics is only 2% of those who are allergic, and 98% of them are toxic reactions.” Since most can not be listed It is very necessary to separate them from unforeseen allergies. Otherwise, the response to non-allergies will not be easy enough to come to the root and lead to the lessons learned. Inflammation of the skin test may be a sensitive reaction may also be a illusion, and the combination of antigen and antibody has nothing to do, but in appearance can not tell. This article intends to combine the literature, a brief description of these issues. First introduced the author in the past encountered several small doses,
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