患者,男,68岁。因“面部皮肤黄染,尿液呈黄色,四肢乏力,进行性消瘦4个月余”入院。患者于2003年7月起发现面部皮肤黄染,尿液呈茶色,四肢乏力,食欲减退,进行性消瘦。无皮肤瘙痒,无发热,当时未引起重视。曾在县医院住院治疗,查体发现,全身皮肤黄染,全身淋巴结无肿大,巩膜中度黄染,各项肝炎病毒血清免疫学检查均为阴性。腹部 B 超:慢性胆囊炎,胆囊多发性 Patient, male, 68 years old. Because of “facial skin yellow dye, urine yellow, weakness, progressive weight loss more than 4 months ” admission. Patients in July 2003 found facial skin yellow dye, brown urine, limb weakness, loss of appetite, progressive weight loss. No skin itching, no fever, did not pay attention. Had hospitalized in the county hospital, physical examination found that the body skin yellow dye, no enlarged lymph nodes, sclera moderate yellow dye, the hepatitis B virus immunological tests were negative. Abdominal B-ultra: chronic cholecystitis, gallbladder multiple