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难治性青光眼是眼科常见病,常见病因包括多次滤过手术失败、新生血管性青光眼、角膜移植术后继发性青光眼等。因其病因复杂,病情多变,治疗手段虽较多,但疗效较差,常因药物耐受、滤过术后瘢痕阻塞通道等导致手术失败。针对难治性青光眼的特征,一些改良术式及联合术式逐渐应用,如复合式小梁切除术、脉络膜上腔引流术、房角金环植入术及全视网膜光凝联合avastin球内注射等。就难治性青光眼的各种治疗方法、临床疗效及术后并发症等进行综述。
Refractory glaucoma is a common ophthalmology, common causes include multiple filtering failure, neovascular glaucoma, secondary glaucoma after corneal transplantation. Because of its complex etiology, changing conditions, although more treatment, but the less effective, often due to drug tolerance, filtration scar after the passage of obstruction leading to surgical failure. Aiming at the characteristics of refractory glaucoma, some modified and combined surgical procedures are gradually applied, such as compound trabeculectomy, suprachoroidal drainage, goniocastrophe implantation and panretinal photocoagulation combined with intra-avastin injection Wait. The treatment of refractory glaucoma, clinical efficacy and postoperative complications were reviewed.