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氯屈膦酸二钠(Clodronatedisodium)是人工合成的焦磷酸类似物,属双膦酸盐类的骨代谢改善剂。对骨组织有选择性吸附作用,通过防止羟磷灰石结晶溶解、减少破骨细胞的数量和直接强力抑制破骨细胞的活性起到抑制骨吸收作用,对各种骨吸收增加的骨代谢疾...
Clodronatedisodium is an artificially synthesized pyrophosphate analogue and is a bisphosphonate bone metabolism ameliorant. Selective adsorption of bone tissue, by preventing the hydroxyapatite crystal dissolution, reducing the number of osteoclasts and direct inhibition of strong osteoclast activity play a role in inhibiting bone resorption, increased bone metabolism of bone disease ...