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作者将11只猪分为四组(4只肾、3只肝、3只脾、1只主动脉对照),采取经左颈动脉,切开、穿刺、选择性插管。术后观察1—91天造影复查后处死。栓塞剂为95%乙醇,剂量为2.2ml/5公斤,在30—45秒内分别注入到靶动脉。作者目的在于研究并发症并评价乙醇是否为一持久性栓塞剂。具有单枝血供器官如肾和脾的大体病理变化表现为极为明显的完全性梗死,无血管再通和侧枝循环形成。肝脏因有侧枝循环,不可能造成肝脏的完全无血供。全部实验动物均未发生象明胶海绵栓塞脾和肝后产生的脓肿形成。以往认为脾动脉栓塞后行脾切除可减少脾脓肿的发病率。作者认为用乙醇
The authors divided 11 pigs into four groups (4 kidneys, 3 livers, 3 spleens, and 1 aortic control). The left carotid artery was used for incision, puncture, and selective intubation. Postoperative 1 to 91 days after the angiography review was executed. The embolizing agent was 95% ethanol with a dose of 2.2 ml/5 kg and was injected into the target artery within 30-45 seconds. The authors aimed to study complications and evaluate whether ethanol is a persistent embolic agent. The gross pathological changes with single blood supply organs such as kidney and spleen showed extremely complete complete infarction without revascularization and formation of collateral circulation. Because of the collateral circulation of the liver, it is impossible to cause a complete absence of blood supply to the liver. All experimental animals did not develop abscess formation following gelatin sponge embolization of the spleen and liver. In the past, splenectomy was considered to reduce the incidence of splenic abscess after splenic artery embolization. The author believes that using ethanol