论文部分内容阅读
为全面评价砷的发育毒性,本研究采用一组行为功能测试方法,观察了孕鼠染砷对仔鼠神经行为发育的影响。实验选NIH种小白鼠。染砷各组孕鼠于妊娠第7～17天、每天一次灌胃给予不同剂量(0.15、0.75、4.50mgAs/kg)的As_2O_3水溶液,溶剂对照组给予蒸馏水。孕鼠自然分娩。结果
In order to comprehensively evaluate the developmental toxicity of arsenic, we used a set of behavioral test to observe the effects of arsenic in pregnant rats on the neurobehavioral development. NIH species experiments selected mice. The arsenic pregnant mice of each group were administered with As2O3 aqueous solution (0.15,0.75,4.50mgAs / kg) by intragastric administration once a day on the 7th to 17th day of pregnancy, and the solvent control group was given distilled water. Pregnant mice naturally give birth. result