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1例53岁女性患者因耐药性肺结核接受乙胺丁醇、吡嗪酰胺、异烟肼和莫西沙星口服联合卷曲霉素肌内注射治疗。治疗11个月后患者出现恶心、呕吐、乏力、四肢无力，逐渐加重，并出现双下肢软瘫。实验室检查示血清钾、钠、钙、磷和镁最低值分别为1.3、128、1.44、0.20和0.38 mmol/L，肌酸激酶（CK）13 517 U/L。患者被诊断为电解质紊乱、横纹肌溶解症。经静脉及口服补充钾、镁、钙和磷及口服螺内酯治疗14 d，患者血钾4.1 mmol/L，血钠141 mmol/L，血钙2.31 mmol/L，血磷1.13 mmol/L，血镁0.67 mmol/L；四肢肌力恢复良好，可自主行走。“,”A 53-year-old female patient received oral ethambutol, pyrazinamide, isoniazid, and moxifloxacin, as well as intramuscular injection of capreomycin for drug-resistant tuberculosis. After 11 months of treatments, the patient developed nausea, vomiting, fatigue, weakness of limbs, gradually aggravating with soft paralysis of both legs. Laboratory tests showed the lowest values of serum potassium, sodium, calcium, phosphorus, and magnesium were 1.3, 128, 1.44, 0.20 and 0.38 mmol/L, respectively and creatine kinase (CK) increased to 13 517 U/L. The patient was diagnosed with electrolyte disorder and rhabdomyolysis. After 14 days of treatments with intravenous and oral supplementation of potassium, magnesium, calcium, and phosphorus, as well as oral spironolactone, the levels of serum potassium, sodium, calcium, phosphorus, and magnesium were 4.1, 141, 2.31, 1.13, and 0.67 mmol/L, respectively. The patient′s muscle strength recovered well and the patient could walk autonomously.