树突状细胞(dendritic cells,DCs)作为机体免疫的启动者和调控者,成为目前医学研究的热点。小鼠髓源性树突状细胞(bone marrow derived dendritic cell,BMDC)作为研究人DC的良好体外模型,其体外诱导技术一直受到重视和关注,近年来该技术发展迅速并得到广泛的应用。本文对常用的体外诱导小鼠髓源性树突状细胞的方法和影响因素的研究作一综述。 Dendritic cells (DCs), as the initiators and regulators of immune system, have become the focus of current medical research. Mouse bone marrow derived dendritic cells (BMDCs), as a good in vitro model for studying human DC, have attracted much attention and attention in vitro. In recent years, the technology has been rapidly developed and widely used. This review summarizes the commonly used methods and factors influencing the induction of mouse mesenchymal dendritic cells in vitro.