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职业接触以苯并 [ａ]芘 (Ｂ[ａ]Ｐ)为代表的多环芳香烃类化合物 (ＰＡＨ)与肿瘤死亡率增加有关联。Ｂ[ａ]Ｐ在体内经各种代谢酶作用生成活化产物苯并 [ａ]芘环氧二醇 (ＢＰＤＥ) ,后者与ＤＮＡ或血清蛋白形成共价加合物 ,可作为接触ＰＡＨ的生物标志物。本研究探讨ＢＰＤＥ血清
Occupational Exposure Polycyclic aromatic hydrocarbons (PAHs), represented by benzo [a] pyrene (B [a] P), are associated with increased cancer mortality. B [a] P is activated in vivo by various metabolic enzymes to form the benzo [a] pyrene epoxy diol (BPDE), which forms a covalent adduct with DNA or serum proteins and acts as a PAH-exposed organism landmark. This study explored BPDE serum