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目的了解泌尿系感染致病菌的变化，选择敏感抗生素，指导临床用药。方法收集从223例泌尿系感染病人中段尿培养所分离出的196株病原菌。结果在泌尿系感染病原菌中，大肠杆菌占40％，球菌占35％～40％，L型菌株占40．8％。对大肠杆菌较敏感的抗生素为复达欣、丁胺卡那、头孢三嗪。对球菌较敏感的抗生素为复达欣、舒氨新、丁胺卡那。结论泌尿系感染致病菌中，大肠杆菌所占比例较以前文献报道的80％下降至40％左右，G+球菌所占比例明显上升。不论急性或慢性泌尿系感染，L型细菌也明显增多。应根据病原菌特点及药敏结果选择用药，避免滥用抗生素，减少耐药菌株。
Objective To understand the changes of pathogenic bacteria in urinary tract infection, select sensitive antibiotics, and guide clinical medication. Methods A total of 196 pathogens isolated from the urine culture of 223 urinary tract infection patients were collected. Results In urinary tract infection pathogens, Escherichia coli accounted for 40%, 35% to 40% of cocci, L-type strains accounted for 40.8%. More sensitive to E. coli antibiotics Fu Daxin, amikacin, ceftriaxone. More sensitive to antibacterial coccidiostat, Shu ammonia new, amikacin. Conclusions The proportion of Escherichia coli in the pathogens causing urinary tract infection decreased from 80% reported in the literature to about 40%, and the proportion of G + cocci increased significantly. Regardless of acute or chronic urinary tract infection, L-type bacteria also significantly increased. Should be based on the characteristics of pathogens and drug susceptibility results choose to avoid abuse of antibiotics, reduce drug-resistant strains.