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目的 探讨短暂性脑缺血发作(TIA)患者血清神经元特异性烯醇化酶(NSE)的变化及临床意义。方法 采用电化学发光免疫测定法(ECLIA)对40例TIA患者血清NSE水平进行检测。结果 TIA患者血清NSE显著升高,和对照组相比有显著性差异(P<0.05)。结论 TIA患者虽在影像学上没有改变,但血清NSE升高,提示存在神经元损害。
Objective To investigate the changes of serum neuron specific enolase (NSE) in patients with transient ischemic attack (TIA) and its clinical significance. Methods Electrochemiluminescence immunoassay (ECLIA) was used to detect serum NSE levels in 40 TIA patients. Results Serum NSE in TIA patients was significantly higher than that in control group (P <0.05). Conclusion Although there is no change in the imaging of TIA patients, serum NSE is elevated, suggesting neuronal damage.