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Aim: To observe the cavernosal nerve function in male diabetic rats. Methods: Thirty-five male adult SD rats were divided randomly into the diabetic group (n=15) and the control group (n=10). In the diabetic group, diabetes was produced by the administration of streptozotocin (63 mg/kg) at a single intraperitoneal dosing. The latent period of reaction and the corpus cavernosal smooth muscle myopotential were observed after giving a single stimulus to the corpus cavernosal nerve. Results: Compared with the controls, the diabetic rats had a longer latent period and a higher myopotential (both P<0.01). Conclusion: Corpus cavernosal nerve dysfunction may play a role in the erectile dysfunction of diabetic rats.
Aim: To observe the cavernosal nerve function in male diabetic rats. Methods: Thirty-five male adult SD rats were divided randomly into the diabetic group (n = 15) and the control group (n = 10). In the diabetic group, diabetes was produced by the administration of streptozotocin (63 mg / kg) at a single intraperitoneal dosing. The latent period of reaction and the corpus cavernosal smooth muscle myopotential were observed after giving a single stimulus to the corpus cavernosal nerve. Results: Compared with the controls , the diabetic rats had a longer latent period and a higher myopotential (both P <0.01). Conclusion: Corpus cavernosal nerve dysfunction may play a role in the erectile dysfunction of diabetic rats.