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目的分析我院痰标本流感嗜血杆菌的分离培养和耐药情况,为临床用药提供依据。方法收集我院收治的50例患者的痰液标本,对其实施流感嗜血杆菌分离处理,并对其实施药敏试验,分析其耐药情况。结果嗜血杆菌菌株对氨苄西林、头孢唑林、头孢呋辛、头孢呋辛酯、头孢曲松、头孢替坦、呋喃妥因和复方新诺明呈现出高耐药。而对亚胺培南、美洛培南阿卡米星、庆大霉素、妥布霉素、环丙沙星和左旋氧氟沙星敏感。结论在对流感嗜血杆菌患者治疗时,需注意到氨苄西林、嗜血杆菌对头孢类、呋喃妥因和复方新诺明等药物有着高耐药特点,并不适合临床使用。
Objective To analyze the isolation, culture and drug resistance of Haemophilus influenzae in our hospital and to provide evidence for clinical use. Methods The sputum samples of 50 patients admitted to our hospital were collected and treated with Haemophilus influenzae. The drug susceptibility test was conducted and the drug resistance was analyzed. Results Haemophilus strains showed high resistance to ampicillin, cefazolin, cefuroxime, cefuroxime axetil, ceftriaxone, cefotetan, nitrofurantoin and cotrimoxazole. While sensitive to imipenem, meropenem, amikacin, gentamicin, tobramycin, ciprofloxacin and levofloxacin. Conclusion In the treatment of Haemophilus influenzae, it should be noted that ampicillin and Haemophilus are highly resistant to cephalosporins, nitrofurantoin and cotrimoxazole and are not suitable for clinical use.