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为了研究甘草多糖(GPS)对人类肝细胞癌肿瘤细胞及其机制的抗肿瘤作用,笔者提取了GPS并且通过苯酚硫酸试验,鲎变形细胞溶解物试验,凝胶渗透色谱法以及红外光谱分析法对其进行了鉴定。GPS能够通过影响肝细胞癌致癌作用中的P53/PI3K/AKT信号通道,产生了肿瘤抑制作用,这个作用可能会对肝细胞癌患者的临床治疗起到疗效。
In order to study the antitumor effect of glycyrrhiza polysaccharides (GPS) on human hepatocellular carcinoma cells and their mechanism, the author extracted GPS and analyzed by phenol-sulfuric acid test, deformable cell lysate test, gel permeation chromatography and infrared spectroscopy It was identified. GPS can induce tumor suppression by affecting the P53 / PI3K / AKT signaling pathway in carcinogenesis of hepatocellular carcinoma, and this effect may be effective in the clinical treatment of patients with hepatocellular carcinoma.