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目的在大肠镜检查中以良好的止痛及镇静作用，增加患者接受检查的依从性，提高检查的成功率。方法将６１９例患者随机分为观察组（３１９例，给予异丙酚及芬太尼静脉麻醉）与对照组（３００例，常规操作），对２组患者的操作时间、检查成功率、检查反应以及检查前、中、后三阶段的血氧饱和度、心率进行观察。结果观察组操作时间、检查成功率、检查反应等方面明显优于对照组（Ｐ＜０．０１），检查前后血氧饱和度和心率的变化与对照组比较差异无显著意义（Ｐ＞０．０５）。结论辅以异丙酚及芬太尼静脉麻醉进行大肠镜检查是安全有效的，为无痛苦大肠镜检查开辟了广阔前景。
Objective In colonoscopy with good analgesic and sedative effects to increase patient compliance with the inspection and improve the success rate of the examination. Methods 619 patients were randomly divided into observation group (319 cases, given propofol and fentanyl intravenous anesthesia) and control group (300 cases, routine operation), the operation time of two groups, the success rate of examination, examination reaction And check before, during and after the three stages of oxygen saturation, heart rate were observed. Results The operation time, the successful rate of examination and the response of the observation group were significantly better than those of the control group (P <0.01). The changes of oxygen saturation and heart rate before and after the operation were not significantly different from those of the control group (P> 0.05). 05). Conclusions The operation of propofol and fentanyl intravenous anesthesia for colonoscopy is safe and effective, which opens up a broad prospect for painless colonoscopy.