为了解决无碳复写纸用的色素,需要对中间体3,3-双-(对-二甲氨基)苯酞(简称孔雀绿内酯)的合成方法进行探讨。早期报道的各种合成方法产率很低,一般不超过30%。1962年森贺等发现在无溶剂存在条件下先将N,N-二甲苯胺和三氯化铝反应成盐,然后加入苯酐反应,得到的产物全部是孔雀绿内酯,产率可达70%。若在N,N-二甲苯 In order to solve the pigment used in carbonless paper, the synthesis of 3,3-bis- (p-dimethylamino) phthalide (referred to as malachite lactone) intermediate is needed. Earlier reports of various synthetic methods yield very low, generally no more than 30%. 1962 Sen He found in the absence of solvents, the first N, N-dimethylaniline and aluminum chloride reaction into salt, and then add phthalic anhydride reaction, the resulting product is all malachite green lactone, the yield of up to 70 %. If in N, N-xylene