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选择120例已经确诊是2型糖尿病的患者作为观察组,同时选择80例同一时期体检健康的人群设置为对照组。对比两组患者中尿微量清蛋白的含量和阳性率。结果尿微量清蛋白在观察组患者中的含量达(57.36±7.54)mg/L,阳性率达47.46%,两项指标都显著性高于对照组(P<0.05);观察组中尿微量清蛋白在病程6~12年患者中的含量达(32.25±4.91)mg/L,阳性率达48.89%,显著高于病程<6年的患者(P<0.05);尿微量清蛋白在病程>12年的2型糖尿病患者中的含量达(78.25±6.92)mg/L,阳性率达85.18%,都显著性高于病程<6年和病程6~12年的患者(P<0.05)。结论可以有效地应用检测尿微量清蛋白含量来早期诊断糖尿病肾病,而且动态检测其水平变化有利于该疾病的临床治疗和病情评估。
A total of 120 patients with confirmed type 2 diabetes mellitus were selected as the observation group and 80 healthy people in the same period were selected as the control group. Urine albumin content and positive rate in two groups were compared. Results The urinary albumin in the observation group was (57.36 ± 7.54) mg / L, the positive rate was 47.46%, both indexes were significantly higher than those in the control group (P <0.05) (32.25 ± 4.91) mg / L, the positive rate was 48.89%, which was significantly higher than that in patients with disease duration <6 years (P <0.05) (78.25 ± 6.92) mg / L in patients with type 2 diabetes in recent years, the positive rate was 85.18%, which were significantly higher than those in patients with 6 years of disease duration and 6 to 12 years of disease duration (P <0.05). Conclusion The detection of urinary albumin in urine can be effectively used in the early diagnosis of diabetic nephropathy. Moreover, the dynamic changes in the level of urine albumin are helpful for the clinical treatment and assessment of the disease.