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目的 :观察血液灌流或血液灌流加血液透析治疗急性有机磷农药中毒的疗效。方法 :灌流组 4 1例病人 ,非灌流组 2 1例病人 ,两组病人予以阿托品、解磷定等综合治疗 ,灌流组在此基础上加用血液灌流或血液灌流+透析的治疗。结果 :灌流组平均住院时间、胆碱脂酶活力恢复时间短于非灌流组 (P <0 .0 5 ) ,灌流组病死率明显低于非灌流组 (P <0 .0 5 )。结论 :血液灌流或血液灌流加血液透析对急性重度有机磷农药中毒疗效显著。
Objective: To observe the effect of hemoperfusion or hemoperfusion and hemodialysis on acute organophosphorus pesticide poisoning. Methods: A total of 41 patients in the perfusion group and 21 in the non-perfusion group were treated with atropine and phos- phamide. The perfusion group was treated with hemoperfusion or hemoperfusion + dialysis. Results: The average duration of hospital stay and the recovery time of cholinesterase activity in perfusion group were shorter than those in non-perfusion group (P <0.05). The mortality in perfusion group was significantly lower than that in non-perfusion group (P <0.05). Conclusion: Hemoperfusion or hemoperfusion and hemodialysis have significant therapeutic effect on acute severe organophosphorus pesticide poisoning.