Spine fracture prevalence at 40 years and older

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BACKGROUND AND OBJECTIVE

Approximately two million Americans experienced osteoporosis related fracture in 2005. This study investigated the prevalence of spine fractures in American adults 40 years of age or older.

METHODS

Data were obtained from the National Health and Nutrition Examination Survey (NHANES), using data collected from a vertebral fracture assessment (VFA) in 2013 to 2014. The VFA was graded by semiquantitative measurement, bone mineral density (BMD) and an osteoporosis questionnaire. The BMDs of the lumbar spine, total hip and femoral neck were determined.

RESULTS

Data were obtained for 1,602 males and 1,728 females. Overall, 5.4% had spine fractures, including 6.2% of the males and 4.6% of the females. The prevalence of fractures was 2.1% among those 40 to 49, 4.2% among those 50 to 59, 5.4% among those 60 to 69, 10.5% among those 70 to 79 years and 18% among those 80 years of age or older. Of those with fractures, the proportion with moderate/severe fracture was higher among those 65 years of age or older (P=0.03). Those with fractures had lower BMIs and BMDs at all sites.

CONCLUSION

This cross-sectional analysis of U.S. adults ages 40 years or greater found that the overall prevalence of fractures was 5.4%, with the risk increased among those with a lower body mass index and a lower bone mineral density.

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