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目的就支气管哮喘与肺炎衣原体感染患者间的发病原因进行探讨。方法 2011年9月～2012年3月在葫芦岛市中心医院呼吸内科住院或门诊诊断出的支气管哮喘以及呼吸系统感染患者,同时选取健康自愿献血者作为对照进行研究。结果自愿献血员组的肺炎衣原体IgG抗体阳性表达率明显低于哮喘组,差异显著(P<0.05);而哮喘组与感染组患者间无显著性差异。实验结果证实,呼吸道感染组患者肺炎衣原体急性感染率与哮喘组患者的感染率无统计学差异,但哮喘组患者感染率显著高于自愿献血员组的感染率(P<0.05)。结论肺炎衣原体患者的感染及重复感染在支气管哮喘患者中比较常见,这对确诊为肺炎衣原体感染的支气管哮喘患者给予抗肺炎衣原体治疗是非常有效的。
Objective To investigate the pathogenesis of bronchial asthma and Chlamydia pneumoniae infection among patients. Methods From September 2011 to March 2012, patients with bronchial asthma and respiratory infections diagnosed in hospital or outpatient department of respiratory medicine in Huludao Central Hospital were studied, and healthy volunteer blood donors were selected as control. Results The positive rate of IgG antibodies against Chlamydia pneumoniae in volunteer blood donors was significantly lower than that in asthma patients (P <0.05). There was no significant difference between the asthma group and the infected patients. The experimental results confirmed that there was no significant difference in the infection rate of C. pneumoniae among patients with respiratory tract infection and the infection rate of patients with asthma, but the infection rate in patients with asthma was significantly higher than that of voluntary donors (P <0.05). Conclusion Infection and repeated infection of Chlamydia pneumoniae patients are more common in patients with bronchial asthma, which is very effective in the treatment of Chlamydia pneumoniae patients with bronchial asthma patients diagnosed as Chlamydia pneumoniae infection.