Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat

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Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a frequent complication in critically ill patients and cause significant mortality.1 Effects of reactive oxygen species (ROS) on alveolar epithelial cells are involved in the pathophysiology of ALI/ARDS.ROS can provoke DNA damage,lipid peroxidation,and activation of various genes coding for proteins involved in inflammation and cell damage.
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