Ｐ５３基因是一种肿瘤抑制基因，对细胞的生长起负性调节作用，其突变失活在肿瘤演进过程中具有重要作用。本文应用免疫组化技术检测了Ｐ５３蛋白在肺癌中的表达，并用图像分析方法测定ＤＮＡ含量，初步探讨两者之间的关系及Ｐ５３蛋白表达的临床病理意义。１材料和方法１... P53 gene is a tumor suppressor gene that negatively regulates cell growth. Mutation inactivation plays an important role in tumor progression. In this paper, the expression of P53 protein in lung cancer was detected by immunohistochemical technique. DNA content was determined by image analysis method. The relationship between the two was preliminarily discussed and the clinicopathological significance of P53 protein expression was also discussed. 1 Materials and Methods 1...