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目的探讨先天性胆总管囊肿肝功能异常的病理基础及临床意义。方法分析80例先天性胆总管囊肿患者的肝功能结果,对其中的36例进行肝病理观察及随访。结果该病患儿肝功能异常的发生率为80%,胆汁淤滞是其病理基础。手术后随胆汁淤滞的解除,肝功能均恢复正常。结论及时手术解除胆道梗阻是改善肝功能的根本途径。
Objective To investigate the pathological basis and clinical significance of hepatic dysfunction in congenital choledochal cyst. Methods The liver function of 80 patients with congenital choledochal cyst was analyzed. The pathological observation and follow-up of 36 cases were performed. Results The incidence of liver dysfunction in children with this disease was 80%, cholestasis is the pathological basis. After surgery with the lifting of cholestasis, liver function returned to normal. Conclusions Timely surgery to relieve biliary obstruction is the fundamental way to improve liver function.