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自1961年美国Guthrie医生开创新生儿筛查已有50年的历史。我国自1981年开始进行新生儿先天性甲状腺功能减低症(以下简称甲低)的筛查,目前全国筛查覆盖率超过60%[1]。大规模开展筛查以后,发现高促甲状腺素(TSH)血症的发生有所增加,部分临床医生形成了一旦发现血TSH高于正常,即加用甲状腺素替代治疗的思维模式,而对于引起高TSH血症的原因、相关检查、治疗方案及转归情况并不重视。临床误读筛查结果导致长期治疗的现象比
It has been 50 years since the American doctor Guthrie started the screening of newborns in 1961. Since 1981, our country has carried out screening of congenital hypothyroidism (hereinafter referred to as hypothyroidism) in neonates. At present, the national screening coverage is over 60% [1]. After large-scale screening, found that elevated thyroxine (TSH) increased incidence of sepsis, some clinicians formed once the blood TSH is higher than normal, that is, with thyroid hormone replacement therapy mode of thinking, High TSH hyperlipidemia, related tests, treatment options and the outcome of the situation does not value. Clinical misreading screening results lead to long-term treatment than the phenomenon