肺癌的预后一直是临床、病理学界关注的问题。长期以来，有许多临床和病理学特征一直被认为是肺癌潜在的预后决定因素。随着肿瘤生物学行为和转移机制的研究进展，越来越多的研究者开始探讨转移相关因素与肺癌预后的关系。肿瘤新生血管、神经细胞粘附分子、ＡＢＨ血型组抗原、组织蛋白酶Ｂ与层粘连蛋白基底膜形成和白介素２等转移相关因素在肺癌转移和预后中的意义已受到重视。 The prognosis of lung cancer has always been a concern in the clinical and pathological community. For a long time, many clinical and pathological features have been considered as potential prognostic factors for lung cancer. With the advancement of the biological behavior and metastasis mechanism of tumors, more and more researchers have begun to explore the relationship between metastasis-related factors and the prognosis of lung cancer. The significance of tumor neovascularization, neural cell adhesion molecules, ABH blood group antigen, cathepsin B and laminin basement membrane formation, and interleukin-2 metastasis-related factors in metastasis and prognosis of lung cancer has received attention.