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目的提高对嗜酸粒细胞增多症的认识。方法对北京协和医院1992-11~2005-02的嗜酸粒细胞增多症患者53例,予以回顾性分析。结果嗜酸粒细胞增多症的病因多种多样,反应性嗜酸粒细胞增多症中包括变态反应、感染、结缔组织疾病、肿瘤、嗜酸粒细胞性胃肠炎、呼吸系统疾病。特发性嗜酸粒细胞增多症18例表现为病程长、多系统累及,淋巴结肿大、脾大以及血栓的发生率高,白细胞、嗜酸粒细胞水平、免疫球蛋白(IgG)、C反应蛋白(CRP)水平较高。结论嗜酸粒细胞增多症的病因分布常广泛,临床表现各异,因此其诊断和鉴别诊断非常重要。
Objective To improve the understanding of eosinophilia. Methods 53 patients with eosinophilia in Peking Union Medical College Hospital from 1992 to 2005 were retrospectively analyzed. Results The etiologies of eosinophilia varied. Reactive eosinophilia included allergies, infections, connective tissue disorders, tumors, eosinophilic gastroenteritis, and respiratory disorders. 18 cases of idiopathic eosinophilia showed long course of disease, multiple system involvement, swollen lymph nodes, splenomegaly and high incidence of thrombosis, leukocyte, eosinophil level, immunoglobulin (IgG), C reaction Protein (CRP) levels higher. Conclusion The etiology of eosinophilia is widespread and has different clinical manifestations. Therefore, its diagnosis and differential diagnosis are very important.