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目的探讨阿奇霉素序贯疗法治疗MPP的临床价值及优越性。方法将86例MPP患儿分为观察组(45例)和对照组(41例),对照组给予红霉素静脉滴注治疗,观察组给予阿奇霉素序贯疗法治疗,观察两组患儿临床症状及体征改善情况,并进行疗效评定。结果观察组治疗总有效率为97.78%,明显高于对照组的82.93%(P<0.05);观察组临床症状和体征消失时间均低于对照组(P<0.05);观察组不良反应发生率为13.33%,明显低于对照组的34.15%(P<0.05)。结论阿奇霉素序贯疗法治疗MPP具有疗效好、见效快、不良反应少等优点,是目前治疗小儿MPP的一种首选方案。
Objective To investigate the clinical value and superiority of sequential therapy of azithromycin in the treatment of MPP. Methods Eighty-six children with MPP were divided into observation group (n = 45) and control group (n = 41). The control group was treated with erythromycin intravenously. The observation group was treated with azithromycin sequential therapy. The clinical symptoms And signs of improvement, and efficacy evaluation. Results The total effective rate of the observation group was 97.78%, which was significantly higher than that of the control group (82.93%, P <0.05). The clinical symptoms and signs disappeared in the observation group were lower than those in the control group (P <0.05) Was 13.33%, which was significantly lower than that of the control group (34.15%, P <0.05). Conclusion Sequential azithromycin treatment of MPP has the advantages of good curative effect, quick response and few adverse reactions. It is the first choice for the treatment of MPP in children.