目的观察并探讨术前新辅助化疗对宫颈癌的临床疗效。方法选取我院符合标准的25例宫颈癌患者作为观察研究对象,全部病例术前均予采用顺铂、长春花碱、博菜霉素联合方案(PVB)化疗2个疗程后行广泛性子宫切除术与盆腔淋巴结清扫术,观察近期疗效。结果经过术前新辅助化疗后的治疗总有效率达%,宫颈局部的肿瘤直径较化疗前均有不同程度的缩小,该差异具有统计学意义(P<0.05)。结论术前新辅助化疗能够有效提高宫颈癌的近期疗效,是安全有效而且耐受性好的新治疗手段,可以有效提高手术切除率与症状改善率,并降低了病理高危因素对患者预后的负面影响,值得在临床中推广应用。 Objective To observe and discuss the clinical effect of neoadjuvant chemotherapy on cervical cancer before operation. Methods Twenty-five cervical cancer patients in our hospital were selected as observational objects. All patients were treated with cisplatin, vinblastine, and bleomycin combined with chemotherapy (PVB) for 2 courses of chemotherapy, followed by extensive hysterectomy Surgery and pelvic lymph node dissection, observation of short-term efficacy. Results After preoperative neoadjuvant chemotherapy, the total effective rate was up to%, and the diameter of cervical local tumor was reduced to some extent compared with that before chemotherapy. The difference was statistically significant (P <0.05). Conclusion Preoperative neoadjuvant chemotherapy can effectively improve the curative effect of cervical cancer, it is safe and effective and well tolerated new treatment, which can effectively improve the rate of surgical resection and symptom improvement, and reduce the risk of pathological factors on the prognosis of patients with negative Impact, it is worth to promote the clinical application.