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目的 评价溶栓治疗对急性心肌梗死(AMI)的近期疗效。方法 对自1989年9月～1998年4月收治的AMI患者906例分别以溶栓冠脉再通、未再通与未溶栓三组的住院病死率及其影响因素作比较。结果 溶栓再通组死亡率明显低于未再通组(5.2％,15.5％,P<0.01)。AMI合并室颤、室速、急性肺水肿、心源性休克的病人,再通组的住院病死率明显低于未再通组(P<0.01)。而溶栓组死亡率与溶栓未再通组死亡率无显著性差别(P>0.05)。结论 溶栓再通对降低住院病死率具有独立的良好作用。
Objective To evaluate the short-term curative effect of thrombolytic therapy on acute myocardial infarction (AMI). Methods A total of 906 patients with AMI admitted to our hospital from September 1989 to April 1998 were enrolled in the study. Their in-hospital mortality and influencing factors were compared between the three groups. Results The mortality of thrombolytic group was significantly lower than that of non-recanalization group (5.2%, 15.5%, P <0.01). In patients with AMI complicated by ventricular fibrillation, ventricular tachycardia, acute pulmonary edema and cardiogenic shock, the in-hospital mortality of the recanalization group was significantly lower than that of the non-recanalization group (P <0.01). There was no significant difference between the thrombolytic group and the thrombolytic group (P> 0.05). Conclusion Thrombolytic recanalization has an independent and good effect on reducing in-hospital mortality.