自从1962年 Goodman 证明外周血中存在造血干细胞以来,不少学者寻找外周血干细胞动员剂。鉴于造血干细胞形态学特征尚未解决,常把给药后外周血中单核样细胞(Mononuclear Cells)数量的增加作为动员造血干细胞效果的指标之一。许多实验结果表明,伤寒杆菌脂多糖、酵母沉渣、植物血凝素、刀豆球蛋白、硫酸葡聚糖(DS)、硫酸聚乙烯(PVSA)、聚甲基丙烯酸(PMAA)等都 Since 1962, Goodman proved that there are peripheral blood hematopoietic stem cells, many scholars looking for peripheral blood stem cell mobilization. In view of morphological characteristics of hematopoietic stem cells have not been resolved, the increase in the number of mononuclear cells in the peripheral blood after administration often used as an indicator of the effect of hematopoietic stem cell mobilization. Many experimental results show that typhoid lipopolysaccharide, yeast sediment, phytohemagglutinin, cong concanavalin, dextran sulfate (DS), polyvinyl sulfate (PVSA), polymethacrylic acid (PMAA)