疟疾作为一种全球性寄生虫病,因其较高的致死率而备受瞩目。目前,全球约28.5亿人面临感染间日疟的风险,间日疟在全世界各地的发病率正日趋增加;由于对间日疟的认识较少和研究手段有限,间日疟的消灭将带来更大的技术挑战。间日疟抗药性的不断蔓延情况令人担忧,本文就间日疟原虫基因多样性及目前发现的间日疟原虫抗药基因突变进行概括介绍。 As a global parasitic disease, malaria attracts much attention due to its high lethality. At present, some 2.85 billion people worldwide are at risk of contracting vivax malaria and the incidence of vivax malaria in all parts of the world is on the rise; the eradication of vivax with malaria is due to less awareness and limited research tools Come bigger technical challenge. The continuing spread of Plasmodium vivax is worrying, and in this paper, a general description of the genetic diversity of Plasmodium vivax and the currently available mutations in Plasmodium vivax resistant genes was presented.