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胃黏膜上皮内瘤变作为胃癌的癌前病变始终是国内外研究的热点。目前普遍认为胃癌发生之前往往经历胃黏膜不典型增生。为了探索二者之间确切的关系,无论是科研还是临床都做了很多研究工作。从其涉及的概念及演变,在分子遗传学水平包括相关基因、癌基因及酶的改变,在临床处理包括随访和治疗等诸多方面都有了新的研究进展,这些都将给临床工作带来极大的指导意义。
Gastric mucosal intraepithelial neoplasia as a precancerous lesion of gastric cancer has always been a hot spot at home and abroad. It is generally believed that gastric cancer often undergo atypical hyperplasia of gastric mucosa before it occurs. In order to explore the exact relationship between the two, both research and clinical have done a lot of research work. From the concepts and evolution involved, new progress has been made in the molecular genetics including the changes of related genes, oncogenes and enzymes in clinical treatment including follow-up and treatment, which will bring clinical work Great guiding significance.