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用放射免疫法测定８８例小细胞肺癌（ＳＣＬＣ）血清铁蛋白（Ｆｔ）、癌胚抗原（ＣＥＡ），阳性率分别为６０．２％和６９．３％。治疗前后Ｆｔ、ＣＥＡ值始终正常或从升高降至正常者其有效率和生存期比较，无显著性差异Ｐ＞０．０５；治疗前Ｆｔ、ＣＥＡ值升高，治疗后无变化或继续升高者的有效率和生存期均不如前二者，Ｐ＜０．０１，Ｐ＜０．０２。治疗后病变缓解者７４例，每２—３月监测，观其Ｆｔ和ＣＥＡ测定值上升与病变复发和／或转移关系，绝大多数（６０％以上）患者在４—９个月中两项指标开始上升，其中多数在其值呈上升趋势后的１—３个月内检出病灶复发和／或转移。监测ＳＣＬＣ患者血清Ｆｔ、ＣＥＡ值可对其疗效、复发和预后进行判断。
88 cases of small cell lung cancer (SCLC) serum ferritin (Ft) and carcinoembryonic antigen (CEA) were detected by radioimmunoassay. The positive rates were 60.2% and 69.3%, respectively. Before and after treatment, Ft and CEA values were normal or decreased from normal to normal. There was no significant difference between their effective rates and survival time. There was no significant difference P>0.05; Ft and CEA values increased before treatment and there was no change or continue to rise after treatment. The efficiency and survival period of the senior were inferior to the former two, P<0.01, P<0.02. Seventy-four patients with remission after treatment were monitored every 2-3 months. The relationship between the increase of Ft and CEA values and the recurrence and/or metastasis of the disease was observed. The vast majority (60%) of the patients were in 2 to 4 months. The index began to rise, and most of them detected recurrence and/or metastasis of the lesion within 1-3 months after its value showed an upward trend. Monitoring the serum Ft, CEA values of SCLC patients can judge its efficacy, recurrence and prognosis.