自Sanes和MacCallum195 2年首先报道 2例胆管癌发病同时合并肝胆管结石以来 ,胆管结石合并胆管癌的现象越来越引起人们的重视。Chijiwa等报道肝内胆管结石合并肝内胆管癌的发生率约为 7.3% ,Kubo等报道为 2 %～10 %。国内报告肝胆管结石发生肝胆管癌为 0 .36 %～10 0 0 %。这 Since Sanes and MacCallum195 first reported 2 cases of cholangiocarcinoma with concurrent hepatolithiasis in 2 years, the phenomenon of bile duct stones with cholangiocarcinoma has drawn more and more attention. Chijiwa et al reported intrahepatic bile duct stones with intrahepatic cholangiocarcinoma incidence of about 7.3%, Kubo et al reported 2% to 10%. Domestic reports of hepatolithiasis occurred hepatolithiasis was 0.36% ~ 100%. This