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目的观察特丁硫磷的中毒症状,选择有效的治疗药物。方法给大鼠特丁硫磷3mg/kg灌胃中毒,出现症状后,立即i.m解磷注射液或 85号急救方,观察给药前后中毒症状、死亡时间,并测定全血乙酸胆碱酯酶(AChE)活力。结果三组急救组方均能有效对抗大鼠特丁硫磷中毒,中毒 AChE活力很快升高到 80%以上;出现肌颤时间明显延长,重复给药后,死亡率明显下降。结论所选组方能迅速控制特丁硫磷中毒大鼠的症状,明显升高中毒AChE活力,提示解磷注射液与85号急救方能有效对抗特丁硫磷中毒。
Objective To observe the symptoms of tetracycline poisoning, select effective treatment drugs. Methods Tebutatin 3mg / kg intragastric administration in rats, symptoms, immediately i. m solution of phosphorus injection or 85 first aid, observation of poisoning symptoms before and after treatment, the time of death, and determination of whole blood AChE activity. Results All three groups of first aid group were able to effectively combat tetbutophosphate poisoning in rats, and the activity of AChE poisoning rapidly increased to more than 80%. The duration of defibrillation was significantly prolonged. After repeated administration, the mortality rate dropped significantly. Conclusion The selected prescription can rapidly control the symptoms of tetethphane poisoning rats, significantly increase the activity of poisoning AChE, suggesting that the solution of phosphorus and injection No. 85 first-aid effective against teichophos poisoning.