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本文从两个方面对胃癌的声像进行了探讨:(1)用灰阶超声直方图测定胃癌与自体胃平滑肌层的AV值,发现胃癌直方图AV值小于平滑肌层的AV值,有显著差异(P<0.001),提示癌灶回声低于平滑肌;(2)光镜下观察胃癌组织,发现场组织内胶原纤维大量增生,各层中以粘膜下层最显著。增生的胶原纤维垂直方向均匀紧密排列,与入射超声束夹角最小;各层内胶原纤维相互连续,使正常胃壁层次中断、境界不清、胃壁的五层超声反射界面消失。因此推测癌灶部位的胃壁增厚、层次中断、境界消失、回声减低等声像表现,与癌内胶原的增生、排列方式及紧密程度密切相关。
This article discusses the sonography of gastric cancer from two aspects: (1) Using gray-scale ultrasound histogram to measure the AV value of gastric cancer and autogenous gastric smooth muscle layer, and found that the histogram AV value of gastric cancer is smaller than the AV value of smooth muscle layer, there are significant differences (P<0.001), suggesting that the echogenicity of the foci was lower than that of the smooth muscle; (2) Observing the gastric cancer tissues under the light microscope, a large number of collagen fibers were found in the field tissue, and the submucosa was most prominent in each layer. The hyperplastic collagen fibers were evenly and closely arranged in the vertical direction, and the angle of incidence with the ultrasonic beam was the smallest; the collagen fibers in each layer were continuous with each other, so that the level of the normal stomach wall was interrupted, the boundary was unclear, and the five-layer ultrasonic reflection interface of the stomach wall disappeared. Therefore, it is presumed that the gastric wall thickening, disruption of the level, disappearance of realm, echo reduction, etc., are closely related to the proliferation, arrangement and tightness of the collagen in the tumor.