弥漫性小无裂细胞淋巴瘤是高度恶性、进展快、死亡率高的肿瘤，常规CHOP方案治愈率仅为３０％左右。IPI评分＞４分的大细胞淋巴瘤单用CHOP方案５年生存率仅２５％。国外发达国家如美国、德国和法国采用短程、高强度化疗使治愈率明显提高犤１～４犦。美国国立癌症研究所对弥漫性 Diffuse small non-cancerous lymphoma is a highly malignant, fast-growing, high-mortality cancer, the conventional CHOP regimen cure rate of only 30%. The 5-year survival rate of large cell lymphoma alone with CHOP with IPI score> 4 is only 25%. Developed countries such as the United States, Germany and France using short-range, high-intensity chemotherapy to significantly improve the cure rate 犤 1 ~ 4 犦. The National Cancer Institute is diffuse