脂蛋白a作为一种特殊的蛋白颗粒，在致动脉粥样硬化过程中起着极其重要的作用。另外，脂蛋白a在预测动脉粥样硬化性心血管疾病的发生、冠状动脉粥样硬化性心脏病（冠心病）的再发、静脉血栓事件的发生以及肾脏移植预后等方面均有重要的临床价值。目前对于脂蛋白 a尚缺乏确实有效地特异性的临床干预措施。该文就脂蛋白a的临床研究进展予以综述。“,”Lipoprotein(a) as a special protein particles, plays a very important role in causing athero-sclerosis.Besides lipoprotein( a) also has important clinical significance in predicting the occurrence of and relapse of atherosclerotic cardiovascular disease,ocurrence of venous thrombosis and prognosis of renal trans-plantation.At present,specific effective clinical interventions for reducing lipoprotein ( a) are still in lack. Here is to make a review of the clinical research progress of lipoprotein(a).