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目前三价锑是一种治疗血吸虫病较有效的药物,但因它是一种有蓄积作用的细胞毒剂,能抑制组织内多种酵素之机能,妨碍细胞呼吸,故在治疗中往往发生程度不一的毒性反应,严重者甚或导致死亡;我们的经验约有90%是由于心肌的损害。这种反应在事前又往往缺乏明显先兆症状,因此在治程中必须提高警惕,慎重处理,才能安全完成治疗。现择要将锑剂对心脏毒性有关问题分述如下,以供参考:
Currently trivalent antimony is a more effective treatment of schistosomiasis drugs, but because it is a cumulative cytotoxic agent that can inhibit the function of many enzymes in the organization, impeding the respiration of cells, it is often the degree of occurrence in the treatment is not One of the toxic reactions, severe cases, or even lead to death; about 90% of our experience is due to myocardial damage. This reaction in the prior often lack of obvious aura symptoms, so in the course of treatment must be vigilant and careful treatment in order to safely complete the treatment. Now choose to antimony agent on cardiac toxicity related issues are described below, for reference: