寄生虫学和其他自然科学一样,都必需坚持科学技术为社会主义建设服务的根本方针,全面贯彻理论联系实际的原则。在医学寄生虫方面,迫切需要开展的工作,就是针对危害农业人口最严重的寄生虫病防治的有关理论和技术问题。而血吸虫病又是最重要、危害最平重的寄生虫病之一。今将其最近进展及奋斗目标综述如下。 1.“F”型药物及其衍生物的研究 F—30066是我国首创的不含锑的治疗血吸虫病的新药。其化学名称为β-(5硝基-2呋喃)丙烯酸异丙胺。对实验血吸虫病有很强的杀虫作用,小白鼠自感染尾蚴当天起,每天口服400毫克/公斤的药量,连服14天,减虫率高达99.5％;口服较大剂量(600—800毫克/公斤),连服3天,减虫率亦可达90％。在临床上对血吸虫病有显著的退热和改善症状的作用。曾对42例急性血吸虫病息者用双盲试验法分别给予F-30066及安慰剂。结果证明,用F-30066的22例在服药前3天最高体温平均 Parasitology, like other natural sciences, must adhere to the fundamental principle that science and technology serve the socialist construction and fully implement the principle of linking theory with practice. In the area of ​​medical parasites, the urgent need is to address the theoretical and technical issues that threaten the prevention and treatment of parasitic diseases, the most serious agricultural population. Schistosomiasis is one of the most important and endangered parasitic diseases. The recent progress and objectives of this struggle are summarized below. 1. “F” Drugs and Their Derivatives Research F-30066 is the first anti-schistosomiasis drug in China. Its chemical name is β- (5-nitro-2-furan) isopropylamine. On the experimental schistosomiasis has a strong insecticidal effect mice from the day of infection of cercariae daily oral 400 mg / kg dose, and even served 14 days, worm reduction rate as high as 99.5%; oral larger doses (600-800 Mg / kg), even for 3 days, the worm reduction rate up to 90%. Schistosomiasis clinically significant fever and improve the role of symptoms. Forty-two cases of acute schistosomiasis were given F-30066 and placebo using a double-blind trial. The results show that 22 cases with F-30066 the highest body temperature 3 days before taking the average