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目的:探讨分析过敏性紫癜(HSP)患儿血小板参数、D-二聚体、纤维蛋白原的变化。方法:对收治的124例HSP患儿资料进行回顾性分析。结果:与对照组相比,HSP患儿急性期PLT、MPV、PCT、PDW、纤维蛋白原、D-二聚体水平均有显著性升高;并过敏性紫癜肾炎(HSPN)组与非HSPN组D-二聚体水平相比有统计学差异(t=2.03,P<0.05)。结论:HSP患儿急性期血液处于高凝状态,持续高水平的血D-二聚体和纤维蛋白原浓度可能与HSP的肾脏并发症有关。
Objective: To investigate the changes of platelet parameters, D-dimer and fibrinogen in children with Henoch-Schonlech purpura (HSP). Methods: A retrospective analysis was performed on the data of 124 children with HSP admitted. Results: Compared with the control group, the levels of PLT, MPV, PCT, PDW, fibrinogen and D-dimer were significantly increased in children with HSP at the acute stage. Compared with non-HSPN group Group D-dimer levels compared to a statistically significant difference (t = 2.03, P <0.05). CONCLUSIONS: The acute phase of HSP in children with hypercoagulable blood state, sustained high levels of blood D-dimer and fibrinogen concentrations may be related to HSP and renal complications.