红细胞6-磷酸葡萄糖脱氢酶(G-6 PD)缺乏是一种遗传性的红细胞酶病,是新生儿遗传性溶血性贫血的最常见原因。以往一般实验室常用高铁血红蛋白还原试验来间接检测 G-6PD 活性,在某些情况下,可出现假阴性及假阳性结果。为了了解新生儿红细胞 G-6PD 缺乏的真实发病率及基因频率分布,我们采用岛津 uv-730微流式紫外分光光度计定量测定 G-6PD 活性,并同时测 The lack of erythrocyte G-6-phosphate dehydrogenase (G-6 PD) is a hereditary erythrocytic enzyme that is the most common cause of hereditary hemolytic anemia in newborns. In the past, methemoglobin reduction tests were commonly used in the general laboratory to indirectly detect G-6PD activity. In some cases, false-negative and false-positive results may occur. In order to understand the true incidence of G-6PD deficiency in neonates and the frequency distribution of G-6PD, we measured G-6PD activity using Shimadzu UV-730 microfluidic UV spectrophotometer