论文部分内容阅读
目的对比分析急性ST段抬高型心肌梗死(STEMI)院前溶栓与院内溶栓治疗的时间、血管再通率、心源性休克及一年内生存率。方法将88例发病12h内的急性ST段抬高型心肌梗死(STEMI)患者随机分为两组,A组46例,为院前溶栓组,B组42例,为院内溶栓组,应用瑞替普酶对其进行静脉溶栓治疗(瑞替普酶20mg间隔30min2次静脉推注;同时配合依诺肝素皮下注射)。结果经统计学处理,A组(院前溶栓组)比B组(院内溶栓组)溶栓时间提前了180±120min,血管再通率提高了12.73%,P<0.05,心源性休克减少了7.55%,P>0.05,一年内生存率提高了12.32%,P<0.05,差异有统计学意义。结论急性ST段抬高型心肌梗死(STEMI),院前溶栓比院内溶栓治疗争取了时间,降低了心源性休克的发生率,提高了血管再通率及生存率。
Objective To compare the time of prethrombolysis and hospital thrombolysis in patients with acute ST-elevation myocardial infarction (STEMI), the rate of recanalization, cardiogenic shock and the one-year survival rate. Methods A total of 88 patients with acute ST-segment elevation myocardial infarction (STEMI) within 12 hours after onset were randomly divided into two groups. Group A (n = 46) received pre-hospital thrombolysis and group B received thrombolytic therapy Reteplase for intravenous thrombolytic therapy (reteplase 20mg interval 30min2 intravenous injection; at the same time with enoxaparin subcutaneous injection). Results After statistical analysis, the thrombolysis time in group A (pre-hospital thrombolysis group) was 180 ± 120 minutes earlier than that in group B (intra-hospital thrombolysis group), and the recanalization rate was increased by 12.73% (P <0.05) Decreased by 7.55%, P> 0.05, the one-year survival rate increased by 12.32%, P <0.05, the difference was statistically significant. Conclusions Acute ST - segment elevation myocardial infarction (STEMI) and prehospital thrombolysis are more effective than intra - hospital thrombolysis in reducing the incidence of cardiogenic shock and improving the rate of recanalization and survival.